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Ndos adjustmnt is ncssay AVODAT in patints with nal impaimnt [s CLINICAL PHAMACOLOGY ].
Dutastid is xtnsivly mtabolizd in humans by th CYP3A4 and CYP3A5 isonzyms. Th ct potnt CYP3A4 inhibitos on dutastid has not bn studid. Bcaus th potntial dug-dug intactions, us caution whn pscibing AVODAT tpatints taking potnt, chonic CYP3A4 nzym inhibitos (.g., itonavi) [s CLINICAL PHAMACOLOGY ].
Th bands listd a tadmaks thi spctiv owns and a not tadmaks th GSK goup companis. Th maks ths bands a not ailiatd with and dnot ndos th GSK goup companis its poducts.
5 alpha-ductas inhibitos may incas th isk dvlopmnt high-gad postat canc. Whth th ct 5 alpha-ductas inhibitos tduc postat volum tial-latd actos impactd th sults ths tials has not bn stablishd.
Th is nspciic antidot dutastid. Tho, in cass suspctd ovdosag, symptomatic and suppotiv tatmnt should b givn as appopiat, taking th long hal-li dutastid intconsidation.
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