Another problem is that of assessing the efficacy of minocycline and the incidence of severe adverse effects relative to other antibacterials commonly used in acne such as tetracycline and erythromycin.

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Get emergency medical help if you have signs of an allergic reaction to minocyclinehivesdifficult breathingswelling in your face or throator a severe skin reactionfeversore throatburning in your eyesskin painred or purple skin rash that spreads and causes blistering and peeling

Blurry vision severe headache joint pain rash hives facial swelling yellow-tinted skin or eyes accompanied by dark urine chest pain severe nausea and vomiting seizures trouble breathing or swallowing increased bleeding or bruising bloody or watery diarrhea.

Throw away any unused medicine after the expiration date on the label has passedUsing expired minocycline can cause damage to your kidneys.

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although rheumatoid arthritis is not an infection, minocycline may improve the signs and symptoms of this disease.