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Information about Norvasc.
Norvasc is medicine that contains the active substance amlodipineIt has been used to treat cardiovascular problems such as hypertensionhigh blood pressureand anginachest pain caused by problems with the blood flow to the heart
HemodynamicsFollowing administration of therapeutic doses to patients with hypertensionNorvasc produces vasodilation resulting in a reduction of supine and standing blood pressuresThese decreases in blood pressure are not accompanied by a significant change in heart rate or plasma catecholamine levels with chronic dosingAlthough the acute intravenous administration of amlodipine decreases arterial blood pressure and increases heart rate in hemodynamic studies of patients with chronic stable anginachronic oral administration of amlodipine in clinical trials did not lead to clinically significant changes in heart rate or blood pressures in normotensive patients with angina.
Psychiatricsexual dysfunctionmale1 and femaleinsomnianervousnessdepressionabnormal dreamsanxietydepersonalization.
Amlodipine may increase systemic exposure of cyclosporine or tacrolimus when co-administeredfrequent monitoring of trough blood levels of cyclosporine and tacrolimus recommendedadjust dose when appropriate.
Your chest pain may become worse when you first start taking Norvasc or when your dose is increasedCall your doctor if your chest pain is severe or ongoing.
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