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The renal effects of celebrex may hasten the progression of renal dysfunction in patients with preexisting renal disease.

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Celebrexcelecoxibis a nonsteroidal anti-inflammatory drugNSAIDCelecoxib works by reducing hormones that cause inflammation and pain in the body.

Avoid the use of Celebrex in patients with a recent MI unless the benefits are expected to outweigh the risk of recurrent CV thrombotic eventsIf Celebrex is used in patients with a recent MImonitor patients for signs of cardiac ischemia.

The available data do not establish the presence or absence of developmental toxicity related to the use of Celebrex.

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clinical studies show that weight gain due to celebrex occurs only in less than 2 percent of people using this drug.