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SSRIs and SNRIs may impair platelet aggregation and increase the risk of bleeding eventsranging from ecchymoseshematomasepistaxispetechiaeand GI hemorrhage to life-threatening hemorrhageconcomitant use of aspirinNSAIDswarfarinother anticoagulantsor other drugs known to affect platelet function may add to this risk.
Pain relief is proven to be significant for at least three months of treatmentHowever treatment should be based on your individual responseLess pain allows you to get back to your daily routineBetter sleep leads to improved quality of lifeMore refreshing sleep may allow muscle tissues to heal.
The most commonly observed adverse reactions in CYMBALTA-treated patientsincidence of at least 5and at least twice the incidence in placebo patientswere nauseadry mouthsomnolenceconstipationdecreased appetiteand hyperhidrosis.
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