The exact mechanism through which danazol increases the levels of c1inh has not been clearly established but this medicine does not possess any progestogenic properties and it has not proved to have any effect on the release of corticotropin by the pituitary or the normal release of cortisol from the adrenal glands.

Information about Danazol.
The following events have been reported in association with the use of Danazol:
Every effort has been made to ensure that the information provided by Cerner MultumIncMultumis accurateup-to-dateand completebut no guarantee is made to that effectDrug information contained herein may be time sensitiveMultum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriateunless specifically indicated otherwiseMultum’s drug information does not endorse drugsdiagnose patients or recommend therapyMultum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement toand not a substitute forthe expertiseskillknowledge and judgment of healthcare practitionersThe absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safeeffective or appropriate for any given patientMultum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum providesThe information contained herein is not intended to cover all possible usesdirectionsprecautionswarningsdrug interactionsallergic reactionsor adverse effectsIf you have questions about the drugs you are takingcheck with your doctornurse or pharmacist.
Danazol comes as a capsule to take by mouthIt usually is taken twice a day for endometriosis or fibrocystic breast diseaseor two or three times a day for hereditary angioedemaFollow the directions on your prescription label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake danazol exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor.
Laboratory TestsDanazol treatment may interfere with laboratory determinations of testosteroneandrostenedione and dehydroepiandrosterone.
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danazol helps me keep my angioedema under control but when i fail to take my regular dosage i understand that i won t be able to stop the treatment as the symptoms come back.