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Safety and efficacy have not been establisheddoses up to 4 mg/kg/day PO have been used off-label for HIV.
Liver diseaseespecially hepatitis B if you are being treated for HIVor if you had a liver transplant;
Coadministration of single doses of lamivudine and sorbitol resulted in a sorbitol dose-dependent reduction in lamivudine exposuresWhen possibleavoid use of sorbitol-containing medicines with lamivudinesee Clinical Pharmacology12.3Consider more frequent monitoring of HBV viral load when chronic coadministration cannot be avoided.
Liver problemsnausearight-sided stomach painitchingtired feelingloss of appetitedark urineclay-colored stoolsjaundiceyellowing of the skin or eyes
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