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Femara can harm an unborn baby or cause birth defectsDo not use if you are pregnant.

Femara is a medicine that contains the active substance letrozoleIt is used as hormonal treatment in postmenopausal women with breast cancer.

This is an investigational studyLetrozole is FDA approved for the treatment of advanced breast cancer and is commercially availableImatinib mesylate is approved for chronic myelogenous leukemia and is being investigated for use in the treatment of breast cancerA total of 45 patients will take part in this studyAll will be enrolled at MDAnderson.

You will take letrozole once a day by mouth and imatinib mesylate twice a day by mouth until intolerable side effects occur or until your tumor grows furtherYou will stop the treatment if your tumor grows or intolerable side effects occur.

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