Clonidine stimulates all three 2 -receptor subtypes with similar potency.

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Your doctor may prescribe a low-salt or low-sodium dietFollow these directions carefully.

Menopause is the time in a woman’s life when menstrual periods permanently stopalso called thechange of lifeMenopause.

Amitriptyline in combination with clonidine enhances the manifestation of corneal lesions in ratssee Toxicology

Clonidine may potentiate the CNS-depressive effects of alcoholbarbiturates or other sedating drugsIf a patient receiving clonidine hydrochloride is also taking tricyclic antidepressantsthe hypotensive effect of clonidine may be reducednecessitating an increase in the clonidine doseIf a patient receiving clonidine is also taking neurolepticsorthostatic regulation disturbancese.gorthostatic hypotensiondizzinessfatiguemay be induced or exacerbated.

No adequatewell-controlled studies have been conducted in pregnant womenClonidine crosses the placental barriersee CLINICAL PHARMACOLOGYPharmacokineticsBecause animal reproduction studies are not always predictive of human responsethis drug should be used during pregnancy only if clearly needed.

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