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The Clozaril Patient Monitoring Service provides for the centralised monitoring of leucocyte and neutrophil counts which is a mandatory requirement for all patients in the UK who are treated with ClozarilThe use of Clozaril is restricted to patients who are registered with the Clozaril Patient Monitoring ServiceIn addition to registering their patientsprescribing physicians must register themselves and a nominated pharmacist with the Clozaril Patient Monitoring ServiceAll Clozaril-treated patients must be under the supervision of an appropriate specialist and supply of Clozaril is restricted to hospital and retail pharmacies registered with the Clozaril Patient Monitoring ServiceClozaril is not sold toor distributed through wholesalers.
Older adults may be more sensitive to the side effects of this drugespecially constipationtrouble urinatingdrowsinessdizzinesslightheadednessand QT prolongationsee aboveDrowsinessdizzinessand lightheadedness can increase the risk of falling.
Clozapine can also cause seizuresespecially in higher dosesLet your doctor or pharmacist know if you have ever had seizuresWhile taking this medicationavoid driving or other activities during which a sudden loss of consciousness could be dangerouse.goperating heavy machineryswimming
Clozaril must be dispensed under strict medical supervision in accordance with official recommendationssee section 4.4
Continue Clozaril treatmentsample blood twice weekly until counts stabilise or increase.
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if you miss a dose of clozaril for more than 2 days, check with your healthcare provider before starting to take it again to make sure you take the correct dose.