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Appropriate studies have not been performed on the relationship of age to the effects of pioglitazone and glimepiride combination in the pediatric populationSafety and efficacy have not been established.

Duetact may not work as well when you use other medicines at the same timeThis includes prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed hereTell your doctor about all medicines you start or stop using.

When switching from individual diabetes drugs to this combination productyour doctor may ask you to check your blood sugar more often to make sure you do not have a sudden attack of low blood sugarhypoglycemic reactionwhen starting this productSee also Side Effects sectionFollow your doctor’s directions carefully.

Although certain medicines should not be used together at allin other cases two different medicines may be used together even if an interaction might occurIn these casesyour doctor may want to change the doseor other precautions may be necessaryWhen you are taking this medicineit is especially important that your healthcare professional know if you are taking any of the medicines listed belowThe following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

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