Do not use sumatriptan if you have used an mao inhibitor such as furazolidone furoxone , isocarboxazid marplan , phenelzine nardil , rasagiline azilect , selegiline eldepryl, emsam, zelapar , or tranylcypromine parnate in the last 14 days.

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Consequentlyit may be useful to inform patientsor their familiesabout the signs and symptoms associated with MAOI induced hypertensive reactionsIn particularpatients should be urged to reportimmediatelyany severe headache or other atypical or unusual symptoms not previously experienced.

No information is available on the effects of gender on the pharmacokinetics of selegiline.

Selegiline is an enzyme blockerMAO inhibitorthat works by slowing the breakdown of certain natural substances in the brainneurotransmitters such as dopaminenorepinephrineand serotonin

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