When coadministering prograf with other substrates and or inhibitors of cyp3a4 that also have the potential to prolong the qt interval, a reduction in prograf dose, frequent monitoring of tacrolimus whole blood concentrations, and monitoring for qt prolongation is recommended.
Information about Prograf.
Prograf should not be used simultaneously with cyclosporinesee DOSAGE AND ADMINISTRATION
The observed trough concentrations described above pertain to oral administration of Prograf onlywhile monitoring Prograf concentrations in patients receiving Prograf injection as a continuous IV infusion may have some utilitythe observed concentrations will not represent comparable exposures to those estimated by the trough concentrations observed in patients on oral therapy.
This is not a complete list of possible side effectsIf you notice other effects not listed abovecontact your doctor or pharmacist.
Tell your healthcare provider about all the medicines you takeand when you start a new medicine or stop taking a medicineincluding prescription and over-the-counter medicinesvitaminsnaturalherbal or nutritional supplementsEspecially tell your healthcare provider if you take:
Grapefruit and grapefruit juice may interact with tacrolimus and lead to unwanted side effectsAvoid the use of grapefruit products while taking Prograf.
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prograf is an immunosuppressant that is used concomitantly with adrenal corticosteroids to prevent or treat rejection of your transplanted organ.