There have been case reports of promethazine abuse.

Information about Promethazine.

It is unknown if promethazine passes into breast milkIt may have undesirable effects on a nursing infantConsult your doctor before breast-feeding.

The generic version of antihistamine PhenerganPromethazine is used for treating allergic reactions and sedating women during labor and before and after surgeryBut it has been linked to numerous side effectsincluding fatal respiratory depression in children and gangrene.

Administration of promethazine HClpromethazine hydrochloridehas been associated with reported cholestatic jaundice.

Hyperexcitability and abnormal movements have been reported in patients following a single administration of promethazine HClpromethazine hydrochlorideConsideration should be given to the discontinuation of promethazine HClpromethazine hydrochlorideand to the use of other drugs if these reactions occurRespiratory depressionnightmaresdeliriumand agitated behavior have also been reported in some of these patients.

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