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Fecal and/or tongue discoloration occurred more commonly in patients given quadruple therapy versus patients given triple therapyRef]

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1Product InformationProtonix I.VpantoprazoleWyeth-Ayerst LaboratoriesPhiladelphiaPA.

Rarelyproton pump inhibitorssuch as pantoprazolehave caused vitamin B-12 deficiencyThe risk is increased if they are taken every day for a long time3 years or longerTell your doctor right away if you develop symptoms of vitamin B-12 deficiencysuch as unusual weaknesssore tongueor numbness/tingling of the hands/feet

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they called his doctor s office but the doctor had left town for two weeks and the backup doctor switched the prescription to protonix.