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Hydroxyurea is a human carcinogenIn patients receiving long-term hydroxyurea for myeloproliferative disorderssecondary leukemia has been reportedSkin cancer has also been reported in patients receiving long-term hydroxyureaAdvise protection from sun exposure and monitor for the development of secondary malignancies.

It is unknown if this medication affects spermIf you plan to father a childdiscuss the risks and benefits of this medication with your doctor.

Hydroxyurea may increase blood uric acid concentrationAlthough no specific dose adjustments are necessary with probenecid or sulfinpyrazoneAnturanehydroxyurea should be used cautiously with uricosuric medications.

There are a number of things you can do to manage the side effects of hydroxyureaTalk to your care team about these recommendationsThey can help you decide what will work best for youThese are some of the most common or important side effects:

For treating cancerDose should be titrated based on individual patient responseCapsules should be swallowed wholeHydroxyurea capsules should be handled with extreme care and disposed of properly because it causes cell damage.

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