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The concomitant use of sarafem with maois intended to treat depression is contraindicated see contraindications and drug interactions under precautions .

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Get emergency medical help if you have any of these signs of an allergic reactionskin rash or hivesdifficulty breathingswelling of your facelipstongueor throat.

Neonates exposed to fluoxetine and other SSRIs or serotonin and norepinephrine reuptake inhibitorsSNRIslate in the third trimester have developed complications requiring prolonged hospitalizationrespiratory supportand tube feedingSuch complications can arise immediately upon deliveryReported clinical findings have included respiratory distresscyanosisapneaseizurestemperature instabilityfeeding difficultyvomitinghypoglycemiahypotoniahypertoniahyperreflexiatremorjitterinessirritabilityand constant cryingThese features are consistent with either a direct toxic effect of SSRIs and SNRIs orpossiblya drug discontinuation syndromeIt should be noted thatin some casesthe clinical picture is consistent with serotonin syndromesee WARNINGS AND PRECAUTIONS

This medication passes into breast milk and may have undesirable effects on a nursing infantConsult your doctor before breast-feeding.

Patients should be cautioned about the risk of serotonin syndrome with the concomitant use of SARAFEM and other serotonergic agents including triptanstricyclic antidepressantsfentanyllithiumtramadolbuspironetryptophanand StJohn’s Wortsee CONTRAINDICATIONSWARNINGS AND PRECAUTIONSand DRUG INTERACTIONS

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