Yes changes in sinemet carbidopa and levodopa dosing can commonly cause stomach symptoms including appetite.

Information about Sinemet.

If it is almost time for your next doseskip the dose you missed and take your next dose when you are meant toOtherwisetake it as soon as you rememberand then go back to taking your tablet(sas you would normally.

Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.

Before initiating treatment with SINEMETadvise patients about the potential to develop drowsiness and ask specifically about factors that may increase the risk for somnolence with SINEMET such as the use of concomitant sedating medications and the presence of sleep disordersConsider discontinuing SINEMET in patients who report significant daytime sleepiness or episodes of falling asleep during activities that require active participatione.gconversationseatingetcIf treatment with SINEMET continuespatients should be advised not to drive and to avoid other potentially dangerous activities that might result in harm if the patients become somnolentThere is insufficient information to establish that dose reduction will eliminate episodes of falling asleep while engaged in activities of daily living.

Before initiating treatment with SINEMETadvise patients about the potential to develop drowsiness and ask specifically about factors that may increase the risk for somnolence with SINEMET such as the use of concomitant sedating medications and the presence of sleep disordersConsider discontinuing SINEMET in patients who report significant daytime sleepiness or episodes of falling asleep during activities that require active participatione.gconversationseatingetcIf treatment with SINEMET continuespatients should be advised not to drive and to avoid other potentially dangerous activities that might result in harm if the patients become somnolentThere is insufficient information to establish that dose reduction will eliminate episodes of falling asleep while engaged in activities of daily living.

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