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I vth edition p-232 and chloroquine.

Malarone and doxycycline – equal endorsement for use in areas where there is chloroquine resistence.

Patients in whom chloroquine or hydroxychloroquine have failed to prevent or cure clinical malaria or parasitemia, or patients who acquired malaria in a geographic area where chloroquine resistance is known to occur should be treated with another form of antimalarial therapy see indications and usage malaria and warnings .