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Another problem is that of assessing the efficacy of minocycline and the incidence of severe adverse effects relative to other antibacterials commonly used in acne such as tetracycline and erythromycin.

Pohle t, menzel j, domschke w minocycline and fulminant hepatic failure necessitating liver transplantation.

Stop taking minocycline hcl er tablets and call your doctor if you have changes in your vision or unusual headaches, or if you get a fever, rash, joint pain or body weakness, as these could be signs of a serious condition.