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Like other topical corticosteroidsclobetasol propionate has anti-inflammatoryantipruriticand vasoconstrictive propertiesThe mechanism of the anti-inflammatory activity of the topical steroidsin generalis unclearHowevercorticosteroids are thought to act by the induction of phospholipase A 2 inhibitory proteinscollectively called lipocortinsIt is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursorarachidonic acidArachidonic acid is released from membrane phospholipids by phospholipase A 2

This medication is used to treat a variety of skin conditionse.gpsoriasiseczemadermatitisallergiesrashClobetasol reduces the swellingitchingand redness that can occur in these types of conditionsIt also can heal the roughscaly patches on the skin seen with psoriasisThis medication is a very strongsuper-high-potencycorticosteroidThis medication also contains emollientsEmollients soften and moisturize the skinleading to decreased itching and flakingEmollients also help to protect the skin against irritation.

During pregnancythis medication should be used only when clearly neededDiscuss the risks and benefits with your doctor.

All drugs may cause side effectsHowevermany people have no side effects or only have minor side effectsCall your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

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