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The most serious side effects seen with FEMARA are bone effectsfracturesdecreased bone density and osteoporosisand increases in cholesterolOther common side effects seen with FEMARA include joint painnauseaweight decreasevaginal irritationand pain in the extremitiesOther important less commonly reported side effects include blood clotsother cancersstrokeheart attack and endometrial cancer.

FEMARA is a once-dailyconvenient prescription tabletYour doctor may tell you to take FEMARA every other day if you have severe liver diseaseAlways take your medicine exactly as prescribed by your doctor.

The optimal duration of treatment with Femara is not knownTreatment should be discontinued if there is a tumor relapse.

You will take letrozole once a day by mouth and imatinib mesylate twice a day by mouth until intolerable side effects occur or until your tumor grows furtherYou will stop the treatment if your tumor grows or intolerable side effects occur.

Some women had moderatetemporary decreases in white blood cell countsThe medical significance of this is not known.

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