The effects of xenical on body mass index bmi and weight loss were assessed in a 54-week multicenter, double-blind, placebo-controlled study in 539 obese adolescents 357 receiving xenical 120 mg three times a day, 182 receiving placebo , aged 12 to 16 years.

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If you take cyclosporinetake it at least 3 hours before or after orlistat to make sure the full dose of cyclosporine is absorbed into your bloodstreamIf you take levothyroxinetake it at least 4 hours before or after orlistat.

There have been rare postmarketing reports of severe liver injury with hepatocellular necrosis or acute hepatic failure in patients treated with XENICALwith some of these cases resulting in liver transplant or deathPatients should be instructed to report any symptoms of hepatic dysfunctionanorexiapruritusjaundicedark urinelight-colored stoolsor right upper quadrant painwhile taking XENICALWhen these symptoms occurXENICAL and other suspect medications should be discontinued immediately and liver function tests and ALT and AST levels obtained.

Table 4 illustrates the percentage of adult patients on XENICAL and placebo who developed a low vitamin level on two or more consecutive visits during 1 and 2 years of therapy in studies in which patients were not previously receiving vitamin supplementation.

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xenical may cause changes in your bowel or stool e.