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The anti-nausea drug Zofran is approved for the prevention of nausea and vomiting caused by cancer chemotherapyradiation and surgeryDoctors also prescribe the medication to treat morning sicknessthough studies offer conflicting results about its potential for causing birth defects.
Serotonin is produced largely in the gastrointestinal tractWhen a patient undergoes cancer treatmentradiation or chemotherapy drugs can cause specialized cells in the intestine to release serotoninZofran and the other 5-HT3 receptor antagonists work by preventing this serotonin from binding to 5-HT3 receptors.
Certain drugs may increase the risk of serious side effects when used with ZofranZuplenz or generic ondansetron.
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